Jan Korabecny Selected Research

chloroacetic acid (chloroacetate)

2/2022

Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.

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Jan Korabecny Research Topics

Disease

39	Alzheimer Disease (Alzheimer's Disease) 09/2022 - 10/2010
7	Neoplasms (Cancer) 10/2022 - 01/2014
5	Poisoning 01/2021 - 01/2010
4	Ataxia Telangiectasia (Louis Bar Syndrome) 10/2022 - 01/2014
3	Amnesia (Dissociative Amnesia) 01/2021 - 01/2018
3	Narcolepsy 10/2020 - 11/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2021 - 01/2021
2	Sleep Initiation and Maintenance Disorders (Insomnia) 10/2020 - 11/2018
2	Amyloid Plaque 01/2019 - 01/2017
2	Sleep Wake Disorders 01/2019 - 11/2018
1	Psychotic Disorders (Schizoaffective Disorder) 03/2022
1	Schizophrenia (Dementia Praecox) 03/2022
1	Mental Disorders (Mental Disorder) 03/2022
1	Paralysis (Palsy) 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Malaria 01/2020
1	Neuroinflammatory Diseases 01/2020
1	Nausea 01/2020
1	Vomiting 01/2020
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2020
1	Organophosphate Poisoning 01/2019
1	Inflammation (Inflammations) 01/2017
1	Cognitive Dysfunction 01/2017
1	Parkinson Disease (Parkinson's Disease) 01/2016

Drug/Important Bio-Agent (IBA)

14	Tacrine (Cognex)FDA Link 07/2021 - 11/2011
12	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2019 - 10/2010
9	Pharmaceutical PreparationsIBA 07/2021 - 01/2017
8	LigandsIBA 03/2022 - 01/2018
6	Phosphotransferases (Kinase)IBA 10/2022 - 01/2014
5	Amyloid (Amyloid Fibrils)IBA 01/2021 - 01/2017
4	AcetylcholinesteraseIBA 01/2021 - 07/2017
4	DNA (Deoxyribonucleic Acid)IBA 09/2018 - 01/2014
3	Cholinesterases (Cholinesterase)IBA 01/2021 - 01/2016
3	OrexinsIBA 10/2020 - 11/2018
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2014
3	Memantine (Namenda)FDA Link 01/2019 - 06/2014
3	Donepezil (Aricept)FDA LinkGeneric 01/2019 - 12/2018
3	Biological ProductsIBA 01/2017 - 02/2013
2	InsecticidesIBA 01/2022 - 01/2020
2	Scopolamine (Hyoscine)FDA Link 01/2021 - 04/2019
2	Therapeutic UsesIBA 01/2021 - 04/2018
2	Tryptophan (L-Tryptophan)FDA Link 01/2021 - 04/2019
2	ButyrylcholinesteraseIBA 12/2020 - 01/2018
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2020 - 01/2017
2	Orexin ReceptorsIBA 10/2020 - 11/2018
2	tabunIBA 01/2019 - 01/2010
2	OximesIBA 01/2019 - 01/2014
2	6-chlorotacrineIBA 01/2019 - 01/2018
2	DNA-Activated Protein KinaseIBA 10/2014 - 01/2014
2	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 10/2014 - 01/2014
1	Cisplatin (Platino)FDA LinkGeneric 10/2022
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 09/2022
1	Serotonin (5 Hydroxytryptamine)IBA 03/2022
1	Serotonin ReceptorsIBA 03/2022
1	N-dodecyl-L-lysine amideIBA 03/2022
1	cariprazineIBA 03/2022
1	Amphetamine (Amfetamine)FDA LinkGeneric 03/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 03/2022
1	Dopamine (Intropin)FDA LinkGeneric 03/2022
1	Antipsychotic Agents (Antipsychotics)IBA 03/2022
1	chloroacetic acid (chloroacetate)IBA 02/2022
1	thiophosgeneIBA 02/2022
1	ChloridesIBA 02/2022
1	amiridine (ipidacrine)IBA 02/2022
1	ThioureaIBA 02/2022
1	nasIBA 01/2022
1	Cholinergic Agents (Cholinergics)IBA 01/2022
1	EnzymesIBA 01/2021
1	Calcium Channels (Calcium Channel)IBA 01/2021
1	Monoamine Oxidase (MAO)IBA 01/2021
1	benzothiazoleIBA 01/2021
1	Glycogen Synthase KinasesIBA 01/2021
1	Organophosphorus CompoundsIBA 01/2021
1	huprine YIBA 01/2021
1	phenothiazineIBA 01/2021
1	indoleIBA 01/2021
1	YNT-185IBA 10/2020
1	BerberineIBA 10/2020
1	Cysteine (L-Cysteine)FDA Link 01/2020
1	berzosertibIBA 01/2020
1	VX (EDIM)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	Nerve AgentsIBA 01/2019
1	isoquinolineIBA 01/2019
1	imidazoleIBA 01/2019
1	Histamine H3 Receptors (Histamine H3 Receptor)IBA 01/2019
1	OrganophosphatesIBA 01/2019
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	AlkaloidsIBA 01/2019
1	AntioxidantsIBA 12/2018
1	Doxorubicin (Adriamycin)FDA LinkGeneric 09/2018
1	tau Proteins (tau Protein)IBA 01/2018
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2018
1	Quinuclidinyl BenzilateIBA 01/2018
1	Trace Elements (Biometals)IBA 01/2017
1	7-methoxytacrine (TA 03)IBA 01/2017
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2016
1	Oxyquinoline (8 Hydroxyquinoline)FDA Link 01/2016

Therapy/Procedure

15	Therapeutics 10/2022 - 01/2014
1	Drug Therapy (Chemotherapy) 01/2020